just sick
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ChickenBong
- Posts: 201
- Joined: Sat Feb 27, 2010 12:39 pm
- Location: eastern oregon, hermiston area
just sick
hey guys still out wtf i had to reregister well iam still going to be out for a few more weeks enjoy all . had some medical problems cancer is showing signs of return..so thats all it new....Chicken Bong
Re: just sick
new forums,
Hey good luck with the cancer. I hope you get better.
Hey good luck with the cancer. I hope you get better.
Re: just sick
hey bro sorry to hear that, hope all goes well kick thats shit in the ass bro, miss killing your sorry ass 
"No bastard ever won a war by dying for his country. He won it by making the other poor dumb bastard die for his country."
~George S. Patton~
~George S. Patton~
Re: just sick
CHICKEN, I miss u brother, stay positive and come back soon......
"Don't SWEAT the PETTY things, and don't PET the SWEATY things"
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PvtTuscany
- Posts: 44
- Joined: Sun Feb 21, 2010 11:54 am
- Location: Austin, Texas
Re: just sick
Chicken Bong - wishing you a speedy recovery to full health. Miss being killed by you.....well, only a little.....
Re: just sick
I'm sorry to hear about your condition I hope things will turn out well for you! It's good to shoot the shit with you in game so come back soon when your feeling better!
Zero Hour
Zero Hour
Re: just sick
Dang... sorry to hear that. Get better soon dude and good luck.
Re: just sick
hope all goes well with ya dude
we'll all be wishing ya the best so we can frag ya in game again soon!
we'll all be wishing ya the best so we can frag ya in game again soon!
[img]http://blitzkrieg.hlstatsx.com/hlstats.php/sig/5988_random.png[/img]
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ChickenBong
- Posts: 201
- Joined: Sat Feb 27, 2010 12:39 pm
- Location: eastern oregon, hermiston area
Re: just sick
Just got back from the Dr and this is what he found..So hopefully soon i will be back about 2 more weeks of this shit i Hope Thanks guys and gals for you careing about me.And takeing your time to see how i am Iam doing better.thanks every body.
Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells.[1] The condition, per its name, involves both aplasia and anemia. Typically, anemia refers to low red blood cell counts, but aplastic anemia patients have lower counts of all three blood cell types: red blood cells, white blood cells, and platelets, termed pancytopenia.
Contents [hide]
1 Causes
2 Signs and symptoms
3 Diagnosis
4 Treatment
5 Prognosis
6 Follow-up
7 Notable cases
8 See also
9 References
10 External links
[edit] Causes
In many cases, the etiology is considered to be idiopathic (cannot be determined), but one known cause is an autoimmune disorder in which white blood cells attack the bone marrow.
Aplastic anemia is also sometimes associated with exposure to toxins such as benzene, or with the use of certain drugs, including chloramphenicol, carbamazepine, felbamate, phenytoin, quinine, and phenylbutazone. Many drugs are associated with aplasia mainly according to case reports but at a very low probability. As an example, chloramphenicol treatment is followed by aplasia in less than 1 in 40,000 treatment courses, and carbamazepine aplasia is even more rare.
Exposure to ionizing radiation from radioactive materials or radiation-producing devices is also associated with the development of aplastic anemia.
Aplastic anemia is present in up to 2% of patients with acute viral hepatitis[citation needed].
In some animals aplastic anemia may have other causes. For example, in the ferret (mustela putorious furo) aplastic anemia is caused by estrogen toxicity. This is because female ferrets are induced ovulators, so mating is required to bring the female out of heat. Intact females, if not mated, will remain in heat, and after some time the high levels of estrogen will cause the bone marrow to stop producing red blood cells
[edit] Signs and symptoms
Anemia with malaise, pallor and associated symptoms such as palpitations
Thrombocytopenia (low platelet counts), leading to increased risk of hemorrhage, bruising and petechiae
Leukopenia (low white blood cell count), leading to increased risk of infection
Reticulocytopenia (low reticulocyte counts)
[edit] Diagnosis
The condition needs to be differentiated from pure red cell aplasia. In aplastic anemia the patient has pancytopenia (i.e., anemia, neutropenia and thrombocytopenia) resulting in decrease of all formed elements. In contrast, pure red cell aplasia is characterized by reduction in red cells only. The diagnosis can only be confirmed on bone marrow examination. Before this procedure is undertaken, a patient will generally have had other blood tests to find diagnostic clues, including a complete blood count (CBC), renal function and electrolytes, liver enzymes, thyroid function tests, vitamin B12 and folic acid levels.
Following tests aid in determining differential diagnosis for aplastic anemia:
Bone marrow aspirate and biopsy: to rule out other causes of pancytopenia (i.e. neoplastic infiltration or significant myelofibrosis).
History of iatrogenic exposure to cytotoxic chemotherapy: can cause transient bone marrow suppression
X-rays, computed tomography (CT) scans, or ultrasound imaging tests: enlarged lymph nodes (sign of lymphoma), kidneys and bones in arms and hands (abnormal in Fanconi anemia)
Chest X-ray: infections
Liver tests: liver diseases
Viral studies: viral infections
Vitamin B12 and folate levels: vitamin deficiency
Blood tests for paroxysmal nocturnal hemoglobinuria
Test for antibodies: immune competency
[edit] Treatment
Treating immune-mediated aplastic anemia involves suppression of the immune system, an effect achieved by daily medicine intake, or, in more severe cases, a bone marrow transplant, a potential cure.[2] The transplanted bone marrow replaces the failing bone marrow cells with new ones from a matching donor. The multipotent stem cells in the bone marrow reconstitute all three blood cell lines, giving the patient a new immune system, red blood cells, and platelets. However, besides the risk of graft failure, there is also a risk that the newly created white blood cells may attack the rest of the body ("graft-versus-host disease").
Medical therapy of aplastic anemia often includes a short course of anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and several months of treatment with ciclosporin to modulate the immune system. Mild chemotherapy with agents such as cyclophosphamide and vincristine may also be effective. Antibody therapy, such as ATG, targets T-cells, which are believed to attack the bone marrow. Steroids are generally ineffective, though are often used to combat serum sickness caused by ATG use.
One prospective study involving cyclophosphamide was terminated early due to a high incidence of mortality, due to severe infections as a result of prolonged neutropenia.[3]
In the past, before the above treatments became available, patients with low leukocyte counts were often confined to a sterile room or bubble (to reduce risk of infections), as in the famed case of Ted DeVita.[4]
[edit] Prognosis
Untreated aplastic anemia is an illness that leads to rapid death, typically within six months. If the disease is diagnosed correctly and initial treatment is begun promptly, then the survival rate for the next five to ten years is substantially improved, and many patients live well beyond that length of time.[citation needed]
Occasionally, milder cases of the disease resolve on their own. Relapses of previously controlled disease are, however, much more common. Relapse following ATG/ciclosporin use can sometimes be treated with a repeated course of therapy.
Well-matched bone marrow transplants from siblings have been successful in young, otherwise healthy people, with a long-term survival rate of 80%-90%. Most successful BMT recipients eventually reach a point where they consider themselves cured for all practical purposes, although they need to be compliant with follow-up care permanently.[citation needed]
Older people (who are generally too frail to undergo bone marrow transplants) and people who are unable to find a good bone marrow match, who undergo immune suppression have five year survival rates of up to 75%.
Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells.[1] The condition, per its name, involves both aplasia and anemia. Typically, anemia refers to low red blood cell counts, but aplastic anemia patients have lower counts of all three blood cell types: red blood cells, white blood cells, and platelets, termed pancytopenia.
Contents [hide]
1 Causes
2 Signs and symptoms
3 Diagnosis
4 Treatment
5 Prognosis
6 Follow-up
7 Notable cases
8 See also
9 References
10 External links
[edit] Causes
In many cases, the etiology is considered to be idiopathic (cannot be determined), but one known cause is an autoimmune disorder in which white blood cells attack the bone marrow.
Aplastic anemia is also sometimes associated with exposure to toxins such as benzene, or with the use of certain drugs, including chloramphenicol, carbamazepine, felbamate, phenytoin, quinine, and phenylbutazone. Many drugs are associated with aplasia mainly according to case reports but at a very low probability. As an example, chloramphenicol treatment is followed by aplasia in less than 1 in 40,000 treatment courses, and carbamazepine aplasia is even more rare.
Exposure to ionizing radiation from radioactive materials or radiation-producing devices is also associated with the development of aplastic anemia.
Aplastic anemia is present in up to 2% of patients with acute viral hepatitis[citation needed].
In some animals aplastic anemia may have other causes. For example, in the ferret (mustela putorious furo) aplastic anemia is caused by estrogen toxicity. This is because female ferrets are induced ovulators, so mating is required to bring the female out of heat. Intact females, if not mated, will remain in heat, and after some time the high levels of estrogen will cause the bone marrow to stop producing red blood cells
[edit] Signs and symptoms
Anemia with malaise, pallor and associated symptoms such as palpitations
Thrombocytopenia (low platelet counts), leading to increased risk of hemorrhage, bruising and petechiae
Leukopenia (low white blood cell count), leading to increased risk of infection
Reticulocytopenia (low reticulocyte counts)
[edit] Diagnosis
The condition needs to be differentiated from pure red cell aplasia. In aplastic anemia the patient has pancytopenia (i.e., anemia, neutropenia and thrombocytopenia) resulting in decrease of all formed elements. In contrast, pure red cell aplasia is characterized by reduction in red cells only. The diagnosis can only be confirmed on bone marrow examination. Before this procedure is undertaken, a patient will generally have had other blood tests to find diagnostic clues, including a complete blood count (CBC), renal function and electrolytes, liver enzymes, thyroid function tests, vitamin B12 and folic acid levels.
Following tests aid in determining differential diagnosis for aplastic anemia:
Bone marrow aspirate and biopsy: to rule out other causes of pancytopenia (i.e. neoplastic infiltration or significant myelofibrosis).
History of iatrogenic exposure to cytotoxic chemotherapy: can cause transient bone marrow suppression
X-rays, computed tomography (CT) scans, or ultrasound imaging tests: enlarged lymph nodes (sign of lymphoma), kidneys and bones in arms and hands (abnormal in Fanconi anemia)
Chest X-ray: infections
Liver tests: liver diseases
Viral studies: viral infections
Vitamin B12 and folate levels: vitamin deficiency
Blood tests for paroxysmal nocturnal hemoglobinuria
Test for antibodies: immune competency
[edit] Treatment
Treating immune-mediated aplastic anemia involves suppression of the immune system, an effect achieved by daily medicine intake, or, in more severe cases, a bone marrow transplant, a potential cure.[2] The transplanted bone marrow replaces the failing bone marrow cells with new ones from a matching donor. The multipotent stem cells in the bone marrow reconstitute all three blood cell lines, giving the patient a new immune system, red blood cells, and platelets. However, besides the risk of graft failure, there is also a risk that the newly created white blood cells may attack the rest of the body ("graft-versus-host disease").
Medical therapy of aplastic anemia often includes a short course of anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and several months of treatment with ciclosporin to modulate the immune system. Mild chemotherapy with agents such as cyclophosphamide and vincristine may also be effective. Antibody therapy, such as ATG, targets T-cells, which are believed to attack the bone marrow. Steroids are generally ineffective, though are often used to combat serum sickness caused by ATG use.
One prospective study involving cyclophosphamide was terminated early due to a high incidence of mortality, due to severe infections as a result of prolonged neutropenia.[3]
In the past, before the above treatments became available, patients with low leukocyte counts were often confined to a sterile room or bubble (to reduce risk of infections), as in the famed case of Ted DeVita.[4]
[edit] Prognosis
Untreated aplastic anemia is an illness that leads to rapid death, typically within six months. If the disease is diagnosed correctly and initial treatment is begun promptly, then the survival rate for the next five to ten years is substantially improved, and many patients live well beyond that length of time.[citation needed]
Occasionally, milder cases of the disease resolve on their own. Relapses of previously controlled disease are, however, much more common. Relapse following ATG/ciclosporin use can sometimes be treated with a repeated course of therapy.
Well-matched bone marrow transplants from siblings have been successful in young, otherwise healthy people, with a long-term survival rate of 80%-90%. Most successful BMT recipients eventually reach a point where they consider themselves cured for all practical purposes, although they need to be compliant with follow-up care permanently.[citation needed]
Older people (who are generally too frail to undergo bone marrow transplants) and people who are unable to find a good bone marrow match, who undergo immune suppression have five year survival rates of up to 75%.
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COUGAR_BAIT
- Posts: 804
- Joined: Fri Jan 22, 2010 12:49 pm
- Location: WA
- Contact:
